By Donald Rudikoff, Steven R Cohen, Noah Scheinfeld

It's envisioned that round 15% of the inhabitants be afflicted by atopic dermatitis or eczematous issues at some point soon of their lifetime, inflicting an important percent of visits to dermatologists, fundamental care physicians, and allergists. regardless of a lot present examine curiosity, the pathophysiology of those problems and their optimal remedy stay doubtful. In Atopic Dermatitis & Eczematous problems, the

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Extra resources for Atopic Dermatitis and Eczematous Disorders

Sample text

A low prevalence (<3%) of Dennie–Morgan infraorbital folds might be attributed to their requirement for a secondary crease in the lower eyelid. 20 of diverse origin and tendency to skin infection. Mevorah et al. (1988) considered Dennie–Morgan folds to be of no diagnostic significance. The childhood phase This phase of AD may simply be an extension of infantile eczema or a recurrence of previous infantile eczema expressed during the first 2 years of life, or it may appear spontaneously in patients who never had infantile eczema.

In addition, the average healing time is higher in egg-sensitive patients who have the most severe form of AD than it is in patients with mild or moderate forms of AD (Ricci et al. 2006). indd 37 37 FACTORS THAT ENHANCE VULNERABILITY TO SENSITIZATION Experimental murine research suggests that exposure to atmospheric pollutants may enhance the IgE immune response (Wüthrich 1989). Passive smoking also has been linked to IgE responsiveness and increased incidence of asthma as a result of chronic airway inflammation and subsequent enhanced sensitization (Kjellman 1981).

Excessive use of chemical household products and frequent washing were associated with an increase in AD in a UK contemporary pediatric population (Sherriff et al. 2002). The role of irritants might be played out against a background of impaired epidermal integrity, perhaps allowing these two factors together to provide a basis for AD. INFECTION The interplay of skin pathogens and inflammatory skin disease has received attention in the past decade. It is possible that skin infection is not just a secondary factor but also a facilitating factor in skin disease.

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