By Fereidoon Shahidi(eds.)
Bio-nanotechnology is the major practical expertise of the twenty first century. it's a fusion of biology and nanotechnology in response to the rules and chemical pathways of residing organisms, and refers back to the practical purposes of biomolecules in nanotechnology. It encompasses the learn, production, and illumination of the connections among structural molecular biology, food and nanotechnology, because the improvement of suggestions of nanotechnology may be guided by means of learning the constitution and serve as of the common nano-molecules present in dwelling cells. Biology bargains a window into the main refined choice of sensible nanostructures that exists.
This ebook is a finished evaluate of the state-of-the-art in bio-nanotechnology with an emphasis at the assorted purposes in nutrition and food sciences, biomedicine, agriculture and different fields. It describes intimately the at present to be had equipment and comprises various references to the first literature, making this the precise “field consultant” for scientists who are looking to discover the attention-grabbing global of bio-nanotechnology. issues of safety relating to those new applied sciences are tested in detail.
The booklet is split into 9 sections – an introductory part, plus:
- Nanotechnology in nutrients and medicine
- Nanotechnology, health and wellbeing and foodstuff know-how applications
- Nanotechnology and different flexible applications
- Nanomaterial manufacturing
- Applications of microscopy and magnetic resonance in nanotechnology
- Applications in bettering bioavailability and controlling pathogens
- Safety, toxicology and regulatory aspects
- Future instructions of bio-nanotechnology
The ebook can be of curiosity to a various diversity of readers in undefined, study and academia, together with biologists, biochemists, foodstuff scientists, nutritionists and well-being professionals.
Chapter 1 Biomedical purposes of Nanomaterials: an summary (pages 1–32): Sunil okay. Singh, Paresh P. Kulkarni and Debabrata Dash
Chapter 2 The problem of Nanotechnology?Derived nutrition: Addressing the troubles of the general public (pages 33–46): Tomiko Yamaguchi
Chapter three Nanotechnology and Public overall healthiness: Contributions, offers, and Premises (pages 47–65): Masami Matsuda, Ayako Goto, Toshio Ogino and Yoshiaki Tanaka
Chapter four useful Nanomaterials for Biomedical examine: specialize in Bio?Functionalization, Biosynthesis, and Biomedical purposes (pages 67–96): Murugan Veerapandian, Sathya Sadhasivam, Ramesh Subbiah and Kyusik Yun
Chapter five an outline of Nanoparticle?Assisted Polymerase Chain response expertise (pages 97–106): Cenchao Shen and Zhizhou Zhang
Chapter 6 A Revolution in Nanomedicines (pages 107–123): Iulian Bobe, Mitsunori Harada and Ichiro Nakatomi
Chapter 7 Nanotechnology for Regenerative drugs (pages 124–140): Yoshikazu Kumashiro, Masayuki Yamato and Teruo Okano
Chapter eight Novel applied sciences for the construction of practical meals (pages 141–162): Jack Appiah Ofori and Yun?Hwa Peggy
Chapter nine Nanomedicine: The Revolution of the large destiny with Tiny drugs (pages 163–178): Danny D. Meetoo
Chapter 10 program of a?Cyclodextrin in Nanomedicinal meals and Cosmetics (pages 179–211): Yukiko Uekaji, Ayako Jo, Akihito Urano and Keiji Terao
Chapter eleven Polymer?Based Nanocomposites for nutrition Packaging functions (pages 212–226): Maurizio Avella, Roberto Avolio, Emilia Di speed, Maria Emanuela Errico, Gennaro Gentile and Maria Grazia Volpe
Chapter 12 Ultrasound?Mediated supply structures: utilizing Nano/Microbubbles or Bubble Liposomes (pages 227–245): Kazuo Maruyama, Ryo Suzuki, Yusuke Oda, Yoko Endo?Takahashi and Yoichi Negishi
Chapter thirteen Nanoprobes and Quantum Dots: making use of Nanotechnology to observe Biology (pages 246–251): Shampa Chatterjee
Chapter 14 stronger Optical Biosensors in keeping with Nanoplasmonics (pages 252–269): Kyujung Kim, Youngjin Oh and Donghyun Kim
Chapter 15 Nano?Biosensors for Mimicking Gustatory and Olfactory Senses (pages 270–291): Kiyoshi Toko, Takeshi Onodera and Yusuke Tahara
Chapter sixteen Nanoparticles Inducing Simultaneous Bioreaction in dwelling Organisms: severe Sizes for Transition of Biointeractive habit (pages 292–303): Fumio Watari
Chapter 17 research of Immunological Reactions to Nanoscale meals: attainable incidence of hypersensitive reaction to Nanoscale nutrients debris (pages 304–310): Eisuke F. Sato, Maki Hashimoto and Masayasu Inoue
Chapter 18 an summary of eco-friendly Nanotechnology (pages 311–354): Kelvii Wei Guo
Chapter 19 Characterization of Biopolymer and Chitosan?Based Nanocomposites with Antimicrobial job (pages 355–382): Jong?Whan Rhim
Chapter 20 Nanotechnology and its Use in Agriculture (pages 383–398): Alejandro Perez?de?Luque and M. Carmen Hermosin
Chapter 21 functions of Polymeric Nanoparticles with Steroids: A evaluation (pages 399–405): Megumu Higaki
Chapter 22 Nanocomposites for foodstuff Packaging: an outline (pages 406–413): Tie Lan
Chapter 23 Nanotechnology in beauty items (pages 414–423): Howard A. Epstein and Alexander Kielbassa
Chapter 24 strength clinical purposes of Fullerenes: an summary (pages 424–441): Seema Thakral and Naveen Kumar Thakral
Chapter 25 Biomedical purposes of Carbon?Based Nanomaterials (pages 443–463): Sunil okay. Singh, Paresh P. Kulkarni and Debabrata Dash
Chapter 26 Carbon Nanotubes and their program to Nanotechnology (pages 464–475): Wojtek Tutak, Sara Reynaud and Rajen B. Patel
Chapter 27 Characterization of Cyclodextrin Nanoparticles as Emulsifi ers (pages 476–486): Hiroyoshi Moriyama, Yoshihiro Saito and Debasis Bagchi
Chapter 28 software of Poly(??Glutamic Acid)?Based Nanoparticles as Antigen supply companies in melanoma Immunotherapy (pages 487–505): Kazuhiko Matsuo, Naoki Okada and Shinsaku Nakagawa
Chapter 29 easy Characterization of Nanobubbles and their strength functions (pages 506–516): Seiichi Oshita and Tsutomu Uchida
Chapter 30 formula and Characterization of Nanodispersions Composed of nutritional fabrics for the supply of Bioactive elements (pages 517–530): Takashi Kuroiwa, Jun Watanabe and Sosaku Ichikawa
Chapter 31 construction of Nanoscale meals utilizing High?Pressure Emulsifi cation know-how (pages 531–541): Kazuyuki Takagi
Chapter 32 construction of Monodisperse effective Dispersions by way of Microchannel/Nanochannel Emulsifi cation (pages 542–556): Isao Kobayashi, Marcos A. Neves, Sosaku Ichikawa and Takashi Kuroiwa
Chapter 33 purposes of Atomic strength Microscopy in nutrients Nanotechnology (pages 557–572): Hiroshi Muramatsu, Jun'ichi Wakayama, Kazumi Tsukamoto and Shigeru Sugiyama
Chapter 34 functions of NMR to Biomolecular platforms of Interactions: an summary (pages 573–591): Shinya Hanashima and Yoshiki Yamaguchi
Chapter 35 Bioavailability and supply of Nutraceuticals and practical meals utilizing Nanotechnology (pages 593–604): Hailong Yu and Qingrong Huang
Chapter 36 Encapsulation of Bioactive Compounds in Micron/Submicron?Sized Dispersions utilizing Microchannel Emulsifi cation or High?Pressure Homogenization (pages 605–618): Marcos A. Neves, Isao Kobayashi, Henelyta S. Ribeiro and Katerina B. Fujiu
Chapter 37 Nanometric?Size supply platforms for Bioactive Compounds for the Nutraceutical and foodstuff Industries (pages 619–666): Francesco Donsi, Mariarenata Sessa and Giovanna Ferrari
Chapter 38 Nanoemulsion know-how for supply of Nutraceuticals and Functional?Food materials (pages 667–696): Luz Sanguansri, Christine M. Oliver and Fernando Leal?Calderon
Chapter 39 Nanotechnology and Nonpolar lively Compounds in sensible meals: An program be aware (pages 697–703): Philip J. Bromley
Chapter forty How criteria tell the law of Bio?nanotechnology (pages 705–719): Martha E. Marrapese
Chapter forty-one FDA and Nanotech: child Steps result in Regulatory Uncertainty (pages 720–732): Raj Bawa
Chapter forty two Toxicity and Environmental dangers of Nanomaterials: An replace (pages 733–748): Paresh C. Ray, Anant Kumar Singh, Dulal Senapati, Zhen Fan and Hongtao Yu
Chapter forty three Nanoparticle–Lung Interactions and Their capability results for Human healthiness (pages 749–775): Craig A. Poland and Martin J. D. Clift
Chapter forty four Bio?Nanotechnology: A trip again to the longer term (pages 777–782): Debasis Bagchi, Manashi Bagchi, Hiroyoshi Moriyama and Fereidoon Shahidi
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3 Dose-dependent inhibition of growth rate (μ) of different bacterial strains by silver nanoparticles. Efforts have been made to understand the underlying molecular mechanism of such antimicrobial actions. In this report we have for the ﬁrst time shown that silver NPs can change the protein proﬁle of bacteria by interacting with protein molecules that are involved in bacterial cell signaling. Bactericidal properties of the NPs are related not only to the direct effects of silver NPs accumulating intracellularly or at the cell membrane, but also to the ionic or dissolved silver derived from NPs, which also possesses signiﬁcant antibacterial properties.
However, it is only in the last 5 years that a new branch of science, known as “nanomedicine,” has emerged as a distinct ﬁeld, and it has since grown exponentially. The late Nobel physicist Richard P. Feynman had the visionary idea that tiny nanorobots could be designed, manufactured, and introduced into the human body to perform cellular repairs at the molecular level. In his prescient 1959 talk, “There’s plenty of room at the bottom,” he proposed using machine tools to make smaller machine tools, which could be used in turn to make still smaller machine tools, and so on all the way down to the atomic level .
Antigen Proteasome MHC class II Peptide ER or ER–endosome ? MHC class I To cell surface Fig. 8 Predicted mechanism of cross-presentation induced by γ-PGA NPs. Antigens encapsulated in γ-PGA NPs enter the DC by endocytosis (phagocytosis and/or macropinocytosis). The γ-PGA-NP-enhanced ER–endosome fusion and conﬁned antigens are retrotranslocated via the ER translocon Sec61 from the fused ER–endosome complex to the cytosol. The released antigens are degraded by cytoplasmic proteasomes and transported to the ER or ER–endosome fusion via TAP, and then the antigen–MHC class I complex is presented on the cell surface.