By Dédée F. Murrell

This scientific case publication serves as an invaluable consultant for dermatologists, internists, kin practitioners, pediatricians, and a person else charged with the care of the outside. The case-based structure distinguishes this paintings from a reference-style textbook, in its place permitting readers to narrate the offered instances to their very own patients.

Clinical situations in Autoimmune Blistering illnesses offers support and perception for clinicians in dealing with this team of great and debilitating pores and skin stipulations, with every one case serving as a springboard for extra pursuit and extra wide education. it's going to let these new to the sphere to start to advance a literacy and competence in autoimmune blistering illnesses, whereas skilled dermatologists will locate new how one can sharpen their diagnostic and remedy skills.

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We have speculated that a classical PV may have been transformed into a localized P Veg of Hallopeau type over time; however pathological examination was not conclusive. 2. Intertriginous areas are usually affected in P Veg and isolated scalp involvement seen in this patient is rarely reported [4]. The grotesque cerebriform appearance of scalp lesions was also exceptional. 3. P Veg lesions in intertriginous areas usually respond to treatment; this was not the case for the scalp lesions in this patient which were intractable with a progressive course despite years of treatment.

Immunoglobulins (IVIG; 2 g/kg of body weight) and an increase of the mycophenolate mofetil dose to 2 g/day (Fig. 2). Daily wound care consisted of antiseptic (polihexanide or alginate hydrogel) and non-adhesive wound dressings. Due to the pain associated with oral food intake, parenteral nutrition was necessary to provide adequate nutritional support. In fact, dehydration, hypovolaemia and electrolyte abnormalities necessitated intravenous fluid replacement of up to 7 l per day. The patient was embedded in an air-fluidized temperature-controlled bed on laminated sheets and synthetic dressings.

What is the most relevant differential diagnosis in this patient? 1. Bullous drug eruption 2. Paraneoplastic pemphigus N. -C. Mook • I. Shimanovich D. Zillikens • E. D. F. 1007/978-3-319-10148-4_5, © Springer International Publishing Switzerland 2015 35 36 N. Schumacher et al. 3. Bullous pemphigoid 4. Staphylococcal scalded skin syndrome 5. Mucous membrane pemphigoid On examination, extensive erosions involving the buccal mucosa, tongue, and hard and soft palate with pseudomembrane formation were seen.

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