By Hywel Williams, Michael Bigby, Andrew Herxheimer, Luigi Naldi, Berthold Rzany, Robert Dellavalle, Yuping Ran, Masutaka Furue

(BMJ Books) affiliate editor, Michael Bigby, is with Harvard clinical college, Boston, MA. Covers the idea that of evidence-based dermatology, the severe appraisal toolbox, universal inflammatory dermis illnesses, infestations, melanoma, hair difficulties, infectious dermis ailments, and extra. Key issues and colour illustrations are integrated.

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The CSG has no financial links with any pharmaceutical companies. How does dermatology benefit from systematic reviews? Dermatology can benefit from systematic reviews in three main ways. • They provide a much more comprehensive literature search than a standard review. 8 • People with skin problems are helped by clinical recommendations. For example, the CSG’s review on “local treatments for cutaneous warts” found that simple topical treatments containing salicylic acid appear to be both effective and safe.

J Am Acad Dermatol 1996;34:555–90. References 16. Hines DC, Goldheizer JW. Clinical investigation: a guide 1. Sackett DL, Rosenberg WM, Gray JA, Haynes RB, to its evaluation. Am J Obstet Gynecol 1969;105:450–87. Richardson WS. Evidence based medicine: what it is and 17. Nisbett R, Ross L. Human Inference: Strategies and what it isn’t. BMJ 1996;312:71–2. 2. Sackett DL, Richardson WS, Rosenberg Q, Haynes RB. Evidence-based Medicine. How to practise and teach EBM. London: Churchill Livingstone, 1997.

Critically appraising that evidence for relevance and validity 4. Applying the results of that appraisal of evidence back to the patient 5. Recording the information for the future Step 1: Asking an answerable structured question Developing a structured question that can be answered requires practice. ”. ”. Such a question includes four key elements: 1. the patient population one wishes to generalise to 2. the intervention 3. its comparator 4. 21 Unless one uses such a structure, it would be easy to waste time discussing and searching for data on the role of diets in preventing atopic disease, the effects of dietary supplements such as fish oil, studies that evaluate only short-term clinical signs, and those that deal with a “rag bag” of different types of eczema in adults and children.

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